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HelpTest Code CLPMG Phospholipid (Cardiolipin) Antibodies, IgG and IgM, Serum
Additional Codes
Internal: 10528
External: CARDIOAB
Beaker: LAB464
Reporting Name
Phospholip Ab (Cardiolip) IgM/IgGUseful For
The following clinical situations:
-Unexplained arterial or venous thrombosis
-A history of pregnancy morbidity defined as 1 or more unexplained deaths of a morphologically normal fetus beyond the 10th week of gestation, 1 or more premature births before 34 weeks of gestation caused by severe preeclampsia or placental insufficiency, or 3 or more unexplained, consecutive spontaneous abortions before the 10th week of gestation with no identifiable maternal hormonal or anatomic, or maternal or paternal chromosomal causes
-Presence of a systemic autoimmune rheumatic disease especially systemic lupus erythematosus
-Presence of an unexplained cutaneous manifestations varying from livedo reticularis to cutaneous necrosis such as leg ulcers
-Unexplained thrombocytopenia
-Possible nonbacterial, thrombotic endocarditis
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| MCLIP | Phospholipid Ab IgM, S | Yes | Yes |
| GCLIP | Phospholipid Ab IgG, S | Yes | Yes |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 21 days | |
| Frozen | 21 days |
Reference Values
MPL refers to IgM phospholipid units. One MPL unit is 1 microgram of IgM antibody.
GPL refers to IgG phospholipid units. One GPL unit is 1 microgram of IgG antibody.
Negative: <15.0 MPL or GPL
Weakly positive: 15.0-39.9 MPL or GPL
Positive: 40.0-79.9 MPL or GPL
Strongly positive: ≥80.0 MPL or GPL
Reference values apply to all ages.
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86147 x 2
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CLPMG | Phospholip Ab (Cardiolip) IgM/IgG | 24319-6 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| GCLIP | Phospholipid Ab IgG, S | 3181-5 |
| MCLIP | Phospholipid Ab IgM, S | 3182-3 |
Report Available
Same day/1 to 2 daysReject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | OK |
| Heat-treated specimen | Reject |
Method Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Forms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-Coagulation Test Request (T753)
-Renal Diagnostics Test Request (T830)
Secondary ID
82976Day(s) Performed
Monday through Saturday